Rheumatology in practice

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Are coxibs really more risky than standard NSAIDs?
RDIP, Volume 5, Number 1.

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in rheumatology practice. They are, however, associated with an increased risk of gastrointestinal (GI) perforations, ulcers and bleeds as well as other GI symptoms, such as dyspepsia. There is currently a debate on whether or not selective COX-2 inhibitors (coxibs) offer any added benefit over standard NSAIDs.

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